BioInsilico.blogspot.com

Here is an Idea: There should be an Idea sharing forum, and below which we can discuss our thoughts about a particular idea given, such as it is practical or not and what will be its effects on us, if implemented. There can be option for upvotes and downvotes. And repetition of Idea should not be allowed.  Similarly, we can make a another subdomain for problem section i.e. people will share there problem faced which can be solved by government. People or experts can give suggestion or necessary steps to be taken by him. Similar type of framework is qoura/ stackoverflow. Please try to make a framework like that.  Also there are many open source frameworks like askbot which I like. It has also read only api, if we want to launch it on a native android app /or we can launch the website inside the app completely like the present Mygov app does. http://meta.stackexchange.com/questions/2267/stack-exchange-clones

News Channel and Politicians: Please stop discussion on Religion Here are some of the true facts: We all are evolved from a common ancestor. Nature don't give us tag of any religion or caste. We tag it. When a child is born we say them, that you belong to this religion otherwise, the child will never know what's religion is. The fact is we all are born different from each other. We have all different kind of DNA, which we all know that is used for forensic science to catch the culprit. (Except the Siamese twins, who have the same set of DNA, even they become different after birth because of environmental factors) Don't we learn anything from the Film like PK. Have we lost our thinking power. Are we just a rote learning machine. If not then why such discussions. Please work for the improvement of all. I request news channel and political parties, don't ever raise the name of religion or caste.

Education System in India and How it can be improved in scientific perspective? Even if we have right for education act, in which children have the right to compulsory education, but one of the thing missing is right for quality education. One of the biggest flaws in our country is there is very less quality education available to the students. And the conditions are same for primary as well as higher education. So what is quality education and how the students are taught now in schools and colleges? Some of the flaws in Indian Education System. 1) The education system I am aware of and what I feel is only 1 out of 7 teachers give quality education to their student. 2) In India, students are taught only to secure good marks and that is the only motto of students and teachers. 3) Students are scared of teachers. Students are not free to ask questions to their teachers. Sometimes I feel, student-teacher relationship is like slave and master. Maybe this is a bit harsh stat...

Intelligence and In search of fundamentals Also view:  Why our universe is mathematical? Break, join and duplicate Quora link:  http://qr.ae/7cdYZh Our DNA is made up of just shuffling of just 4 bits of information ATGC and from it, we get the whole DNA and then the whole cell and finally an organism with a brain that has intelligence. It may be analogous to our computer made up of 0's and 1's. Most of the algorithm of today make use of mathematics, that is an addition, subtraction, multiplication or division. But what living organisms do? Can they do mathematics? I don't think so. The small bits of information just duplicate, break and join to produce new information. It may be DNA, mRNA, proteins or microRNAs The same way perhaps our brain works, give some information to the brain, it will join it, break it or duplicate it to produce new information. e.g. Our alphabets: A-Z, from the shuffling of it, we get words and then sentences. A note o...

It has been long thought that (As in Mendelian genetics) parental origin of gene does not affect its expression. With respect to autosomal genes, male and female contribute equal number of genes and produce similar effects. But expression of some genes is significantly affected by the parental type, i.e. whether it came from male or female. This phenomenon is called Genomic Imprinting. One of the example of genomic imprinting is Igf2 (Insulin like growth factor II). It is present in both mice and humans and in both cases genomic imprinting takes place. A child inherit one allele from male parent and other allele from female parent. The paternal copy of Igf2 is actively expressed in the fetus and placenta but maternal copy remains completely silent. So, when the paternal copy is deleted in the mice, the mice produces small placenta and low weight baby. Another example would be Prader-Willi and Angelman syndromes. A child with Prader-Willi...

Hidden Markov Models Hidden Markov Models is one of the popular machines learning approach that can be used to decipher highly complex biological data. One example would be CG-Island. CG is the least frequent nucleotide in many genomes Reason: C within CG is easily methylated Resulting methylation has tendency to mutate into T However methylation is suppressed around genes in areas called CG-Island. Here CG appears relatively frequently. Fair Bet Casino: Through it CG-Islands can be modeled. Dealer flips coin and player bets on outcome: heads or tails Dealer uses either a biased coin (head with probability ¾) or fair coin head or tail equally likely Given a sequence of coin tosses, problem to find out when dealer used a biased coin or a fair coin Obviously, if you observe long line of heads it’s likely that dealer used biased coin and if you observe even distribution of heads and tails he likely used fair one.

Millennium Prize Problems are seven problems in mathematics that were stated by Clay Mathematics Institute in 2000 Out of the 7 problems, one (Poincare conjecture)  problem has been solved If some one solves any of the problem, he is awarded with US $1,000,000 prize Poincare conjecture problem was solved by Grigori Perelman on year 2010,  but he declined  to receive the prize. The seven problems are: P versus NP problem Hodge conjecture Poincare conjecture (solved) Riemann hypothesis Yang-Mills existence and mass gap Navier-Stokes existence and smoothness Birch and Swinnertori-Dyer conjecture P versus NP Problem What is P? This class of problem are easy to solve. We can have algorithm to solve this type of problem within a reasonable amount of time. e.g. Check whether a particular number exists in a list. The simplest solution would be "linear search" algorithm, we check each number in turn until we find th...